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ovarian follicle

anatomy
Also known as: graafian follicle

Quick Summary

An ovarian follicle is a small, fluid-filled sac within the ovary that contains a developing egg cell, or ovum. These follicles are crucial for female reproduction, housing the ova from birth until they mature and are released during ovulation.12345

Ovarian Follicle Development

  • Primordial Follicles: At birth, a female has hundreds of thousands of these undeveloped follicles, each containing a primary ovum.31
  • Maturation: Stimulated by hormones like follicle-stimulating hormone (FSH) from the pituitary gland, a follicle matures over about four months.465
  • Ovulation: When mature, the follicle ruptures, releasing the ovum from the ovary. This process is called ovulation and typically occurs once per menstrual cycle.4

If the ovum is not fertilized within 24 hours of ovulation, it degenerates. The remaining follicular cells form the corpus luteum, which secretes hormones to prepare the uterus for potential pregnancy.45

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