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Osteoid is the unmineralized organic matrix of bone, primarily composed of collagen and other proteins. It is secreted by specialized bone-forming cells called osteoblasts. This gelatinous substance serves as a framework upon which inorganic salts are deposited, leading to the hardening of bone through a process called mineralization. Osteoid is a crucial component in both initial bone formation and the continuous process of bone remodeling throughout life.123

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