opsonin
biochemistry
Also known as: opsonization
Quick Summary
Pathways of complement activation
The main function of complement proteins is to aid in the destruction of pathogens by piercing their outer membranes (cell lysis) or by making them more attractive to phagocytic cells such as macrophages (a process known as opsonization). Some complement components also promote inflammation by stimulating cells to release histamine and by attracting phagocytic cells to the site of infection.
An opsonin is a protein that enhances the ability of phagocytes, such as macrophages, to engulf and destroy foreign particles like bacteria. These proteins act as a tag, making the foreign particle more recognizable and attractive to phagocytic cells.12
Key points about opsonins:
* They include antibodies and complement proteins.1
* Their action is crucial for the immune system's defense against pathogens.2
* The process of coating a microbe with opsonins is called opsonization.2
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