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opioid use disorder
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opioid use disorder

medical condition
Also known as: OUD
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Quick Summary

Opioid use disorder (OUD) is a medical condition characterized by addiction to opioid drugs. These drugs, derived from the opium poppy, include prescription pain relievers like oxycodone and illegal substances such as heroin. Opioids work by interacting with opioid receptors in the brain, producing pain relief and euphoria, but also leading to a high potential for addiction.123

OUD can develop through tolerance and physical dependence, where the body adapts to the substance and experiences withdrawal symptoms if use stops. Addiction involves compulsive use despite harmful consequences and changes in brain pathways related to reward and self-control. Treatment, known as medication for opioid use disorder (MOUD), includes medications like buprenorphine and methadone, which help reduce cravings and withdrawal symptoms.4521

Summary created from Britannica articles using AI. AI can make mistakes, so verify using Britannica articles.
7 Britannica Sources
  1. medication for opioid use disorder
  2. What Is the Difference Between Dependence and Addiction?
  3. drug use - Physiological effects of addiction
  4. How the Opioid Crisis Devastated Families, Communities, and, Ultimately, a Country - The epidemic
  5. substance use disorder
  6. The U.S. Opioid Epidemic
  7. opioid

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