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Olfactory neuroblastoma is a highly malignant tumor originating in the olfactory receptor cells in the upper rear part of the nose. It is a type of neuroblastoma, which is a tumor of the sympathetic nervous system that primarily affects young children. Neuroblastomas are the most common pediatric solid tumors occurring outside the brain.123

While neuroblastoma can arise in various locations, olfactory neuroblastoma specifically develops in the nasal cavity. This particular type of tumor is notable for being one of the few that can often be eradicated with radiation treatment.12

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