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non-Hodgkin lymphoma
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Infographic with pie charts and bar graphs showing projected cancer incidence and mortality in the U.S. for 2025. Key cancers include breast, prostate, lung, and colon, with breakdowns by sex and cancer type. Lung cancer leads in deaths for both men and women.
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non-Hodgkin lymphoma

pathology
Also known as: lymphocytic lymphoma, non-Hodgkins lymphoma
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Infographic with pie charts and bar graphs showing projected cancer incidence and mortality in the U.S. for 2025. Key cancers include breast, prostate, lung, and colon, with breakdowns by sex and cancer type. Lung cancer leads in deaths for both men and women.
Cancer incidence and mortality in the United States Overall cancer mortality in the United States has dropped consistently since the early 2000s, driven mostly by sharp declines in smoking-related cancers. However, incidence trends differ—falling in men but rising slightly in women.

Non-Hodgkin lymphoma is a type of malignant tumor that affects lymphocytes, which are a type of white blood cell. Unlike Hodgkin disease, non-Hodgkin lymphoma typically does not present with a leukemic blood picture. Instead, it is characterized by the enlargement of lymph nodes, spleen, or both.12

Non-Hodgkin lymphomas can arise from either B lymphocytes or T lymphocytes and may progress slowly (indolent) or aggressively. Some types, like diffuse large-cell lymphomas, can spread to organs such as the liver, lungs, kidneys, and brain. While Hodgkin disease often has a high cure rate, non-Hodgkin lymphomas can be more challenging to treat. Viruses have been implicated in causing lymphoma in animals, and a human retrovirus, HTLV-I, is suggested as a cause for T-cell lymphoma. Diagnosis involves laboratory analysis of tissue, usually from lymph nodes.21

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  1. lymphoma
  2. blood disease - Lymphoma

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