negative feedback

biology

Written by

The Information Architects of Encyclopaedia Britannica

Last updated

July 1, 2026

Quick Summary

In biology, negative feedback is a self-regulating process that helps maintain stability within a system, a concept known as homeostasis. This means that the output of a biological reaction influences its own continuation, typically by dampening or reducing the initial process.123

For example, in the human body, if body temperature rises above a set point, negative feedback mechanisms are triggered to lower it. This can involve actions like sweating and increased blood flow to the skin to dissipate heat. Similarly, if blood glucose levels get too high after eating, the hormone insulin is released, which helps cells take up glucose, thus lowering blood sugar levels. These processes ensure that conditions remain within a range optimal for survival.14

Summary created from Britannica articles using AI. AI can make mistakes, so verify using Britannica articles.

5 Britannica Sources

Ask Britannica AI about this topic

Britannica doesn't have a full article on this topic, so we've curated a list of our relevant coverage.

metabolism
Fine control
By this so-called negative feedback system, the cellular concentrations of products determine the rates of their formation, thus ensuring that the cell synthesizes only as much of the products as it needs.
Read More
By this so-called negative feedback system, the cellular concentrations of products determine the rates of their formation, thus ensuring that the cell synthesizes only as much of the products as it needs.
Read More