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monocyte, type of white blood cell that is a critical part of the innate immune system, which is present from birth and provides rapid nonspecific defense against foreign agents. Monocytes account for between 2 and 8 percent of the total number of white blood cells in the body. Although they primarily combat infection and inflammation, monocytes may also contribute to the pathogenesis of certain diseases, especially when present in abnormally high numbers. Consequently, monocyte profiling...