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The mesohyl is an amorphous, gelatinous substance found in sponges that contains various cells, fibers, and skeletal elements. It is not a definite organ but rather a matrix that supports the sponge's structure and functions.1

Key components within the mesohyl include:
* Cells: Archaeocytes, which are amoeboid and can transform into other cell types, play roles in regeneration, food transport, and potentially reproduction. Collencytes secrete fibers, while sclerocytes produce skeletal spicules.21
* Skeletal elements: Sponges can have mineral skeletons made of calcium carbonate or silica in the form of spicules, or they can be composed of spongin, a proteinaceous material. Some sponges lack skeletons entirely.34
* Function: The mesohyl facilitates the movement of water through the sponge's canal system, which is crucial for bringing in food and oxygen, and for removing waste products. It also houses specialized cells that contribute to the sponge's skeleton and defense.541

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