megalencephaly
Quick Summary
Megalencephaly, also known as macrencephaly, is a condition characterized by an abnormally large and heavy brain. This occurs due to issues with cell growth and production, leading to increased cell size and number. The head may be enlarged at birth or become so as the child develops. This condition is more common in males and is associated with developmental delays and seizures.1
It is important to distinguish megalencephaly from microcephaly, which is a condition where the head is smaller than average for the individual's age and sex, often due to the brain not growing properly.2
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