liquid-liquid chromatography
Quick Summary
Liquid chromatography (LC) is a separation technique that uses a liquid mobile phase to separate components of a mixture. In liquid-liquid chromatography (LLC), both the mobile and stationary phases are liquids. A variation, high-performance liquid chromatography (HPLC), uses small particles with bonded molecules to create a thin film with liquid-like properties. Reverse-phase liquid chromatography is a type of HPLC where a nonpolar molecule is bonded to the solid surface, and a polar mobile phase is used. The separation in chromatography is based on the differential distribution of solutes between the mobile and stationary phases, leading to different migration rates and thus separation.123
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