Britannica AI Icon

limb-girdle dystrophy

pathology
Also known as: limb-girdle muscular dystrophy

Quick Summary

Limb-girdle muscular dystrophy is a type of muscular dystrophy, a group of inherited conditions causing progressive muscle weakness and degeneration. This specific type affects the muscles of the pelvic and shoulder girdles. Symptoms typically begin in late childhood, with weakness first appearing in the pelvic region and eventually progressing to the arms and legs. Individuals may experience frequent falling, difficulty climbing, and a waddling gait. Inheritance patterns for limb-girdle muscular dystrophy are usually autosomal recessive, meaning both parents must carry the affected gene for the disease to manifest. While there is no cure, treatments focus on managing symptoms through physical therapy, supportive devices, and medications.123

Summary created from Britannica articles using AI. AI can make mistakes, so verify using Britannica articles.

Ask Britannica AI about this topic

Britannica doesn't have a full article on this topic, so we've curated a list of our relevant coverage.