lactate dehydrogenase

chemical compound

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June 30, 2026

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Lactate dehydrogenase (LDH), also known as lactic dehydrogenase, is an enzyme that plays a crucial role in cellular metabolism. It facilitates the conversion of pyruvate to lactate and back again, a process that is essential for regenerating NAD+ during anaerobic respiration. This regeneration allows glycolysis to continue, producing ATP even when oxygen is scarce. LDH is found in the cytoplasm of most living cells.12

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metabolism
The formation of ATP
… via a reaction catalyzed by lactate dehydrogenase (reaction 11a]); i.e., NADH gives up its hydrogen atoms or electrons to pyruvate, and lactate and NAD⁺ are formed.
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… via a reaction catalyzed by lactate dehydrogenase (reaction 11a]); i.e., NADH gives up its hydrogen atoms or electrons to pyruvate, and lactate and NAD⁺ are formed.
Read More