juxtaglomerular cell
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Juxtaglomerular cells are specialized cells located in the walls of afferent arterioles, which are small arteries leading to the glomeruli in the kidneys. These cells are part of the juxtaglomerular apparatus (JGA) and contain granules that store renin, an enzyme crucial for regulating blood pressure.123
When blood flow to the kidneys decreases, the juxtaglomerular cells release renin into the bloodstream. Renin initiates a cascade that leads to the production of angiotensin II, a potent vasoconstrictor that raises blood pressure. Angiotensin II also stimulates the adrenal glands to release aldosterone, a hormone that promotes sodium and water reabsorption by the kidneys, further contributing to blood pressure regulation. This intricate system, known as the renin-angiotensin system, plays a vital role in maintaining cardiovascular homeostasis.324
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renal systemArteries and arterioles…composite structure is called the juxtaglomerular apparatus (JGA) and is believed to be involved in the secretion of renin (see below The role of hormones in renal function). They are then reconstituted near the point of entry of the afferent arteriole to become the efferent arterioles carrying blood away from…
Read More…composite structure is called the juxtaglomerular apparatus (JGA) and is believed to be involved in the secretion of renin (see below The role of hormones in renal function). They are then reconstituted near the point of entry of the afferent arteriole to become the efferent arterioles carrying blood away from…
Read More- renal systemThe role of hormones in renal function
The juxtaglomerular apparatus (JGA), consisting of an asymmetrical cuff of large granular cells in the wall of the afferent arteriole near its entry into the capsule of the nephron, contains renin in the granules in the cells. Renin is a true internal secretion of the kidney.…
Read MoreThe juxtaglomerular apparatus (JGA), consisting of an asymmetrical cuff of large granular cells in the wall of the afferent arteriole near its entry into the capsule of the nephron, contains renin in the granules in the cells. Renin is a true internal secretion of the kidney.…
Read More