interference removal
Quick Summary
In chemistry, interference removal is a crucial step in chemical analysis. An interference is any substance, other than the target analyte, that can be measured by the analytical method or prevent the analyte from being measured, leading to inaccurate results.123
Several methods exist to remove these interferences, including:
- Complexation: A chemical agent is added to form a complex with the interfering substance, altering its chemical nature so it no longer interferes with the assay.1
- Selective Precipitation: A reagent is used to react with the interference, forming a precipitate that can then be physically separated, often by filtration.2
- Chromatography: This technique separates components of a mixture based on their differing attractions to a stationary phase as a mobile phase moves through it.3
Other methods include distillation, filtration, extraction, and electrogravimetry. Some of these techniques can also be used to perform the actual assay.123
Ask Britannica AI about this topic
Britannica doesn't have a full article on this topic, so we've curated a list of our relevant coverage.
chemical analysisInterference removalRegardless of whether a classical or instrumental method is used, it may be necessary to remove interferences from an analyte prior to an assay. An interference is a substance, other than the assayed material, that can be measured by the chosen analytical method…
Read MoreRegardless of whether a classical or instrumental method is used, it may be necessary to remove interferences from an analyte prior to an assay. An interference is a substance, other than the assayed material, that can be measured by the chosen analytical method…
Read More- separation and purificationReasons for making separations
…impurities in a sample may interfere with the analysis of the substance of primary interest. Thus, in the analysis of trace concentrations of metals in rivers, organic substances can cause erroneous results. These interferences must be removed prior to the analysis. Several techniques for removing interferences are discussed in analysis:…
Read More…impurities in a sample may interfere with the analysis of the substance of primary interest. Thus, in the analysis of trace concentrations of metals in rivers, organic substances can cause erroneous results. These interferences must be removed prior to the analysis. Several techniques for removing interferences are discussed in analysis:…
Read More