insulin-like growth factor 2

…gene known as IGF2 (insulin-like growth factor 2), for instance, has been linked to an increased risk for certain types of cancer, including colorectal cancer and nephroblastoma. Other products of regulatory genes, such as microRNAs, have also been implicated in the malignant transformation of cells, and it is likely…

…are two IGFs: IGF-1 and IGF-2. These two factors, despite the similarity of their names, are distinguishable in terms of specific actions on tissues because they bind to and activate different receptors. The major action of IGFs is on cell growth. Indeed, most of the actions of pituitary growth hormone…