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In medicine, an injection is a method of delivering substances into the body, often through a hollow needle. This technique, known as a shot, allows for direct administration into the bloodstream, ensuring rapid and reliable drug action.12

Historically, the understanding that medications must reach diseased tissues for effectiveness was not always clear. The development of the hollow hypodermic needle in 1853 by Charles Gabriel Pravaz revolutionized drug administration. This innovation, first used therapeutically by Alexander Wood, enabled drugs to be injected directly into the bloodstream, significantly advancing the science of pharmaceutics and dosage form development.3

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