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An icosahedral virus is a type of virus with a symmetrical, polygonal structure, resembling a geodesic dome. This shape is formed by 20 equilateral triangles, each made of protein subunits called capsomeres. At each of the 12 vertices of this structure, there is a penton, composed of five subunits.12

These viruses exhibit three axes of rotational symmetry: fivefold, threefold, and twofold. The size of icosahedral viruses can vary, typically ranging from 20 to 150 nm in diameter, and this size is generally proportional to the amount of nucleic acid coiled inside the virion. Examples of viruses with icosahedral symmetry include adenoviruses and herpesviruses.13

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