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hypokalemic periodic paralysis

pathology
Also known as: familial periodic paralysis

Quick Summary

Hypokalemic periodic paralysis is a rare, inherited disorder characterized by recurrent attacks of muscle weakness, primarily affecting the legs. These attacks, which can last from half an hour to 24 hours, often occur after rest following strenuous exercise. During an attack, blood potassium levels drop, and the affected muscles may become slightly swollen and tender. The condition is caused by mutations in the calcium channel gene. While not typically fatal, the temporary incapacity can be severe. Treatment may involve medications that alter potassium levels, such as acetazolamide.12

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