hyperkalemic periodic paralysis
Quick Summary
Hyperkalemic periodic paralysis is a rare, inherited disorder characterized by recurrent attacks of muscle weakness. Unlike hypokalemic periodic paralysis, where blood potassium levels drop during an attack, hyperkalemic periodic paralysis is associated with an increase in potassium. These attacks, which can be triggered by consuming potassium, typically last minutes to hours and may be accompanied by mild muscle spasms. The condition is caused by mutations in the sodium channel gene on chromosome 17. While generally not fatal, the temporary incapacity can be severe. Treatment may involve medications that alter potassium levels, such as acetazolamide.12
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