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hyperimmune serum globulin
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hyperimmune serum globulin

biology
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Quick Summary

Hyperimmune serum globulin (HISG) is a biological therapy derived from the plasma of individuals with high levels of specific antibodies. It is prepared similarly to general immune serum globulin but uses plasma from donors selected for their elevated antibody titers against particular diseases.1

HISG provides passive immunity, offering temporary protection against various infections. It is used to prevent diseases such as hepatitis B, tetanus, rabies, and varicella-zoster (chickenpox or shingles) in individuals who have been exposed. Rh-immune globulin, a type of hyperimmune serum globulin, is administered to Rh-negative pregnant women to prevent hemolytic disease in newborns.1

Human immune serum globulin (HISG) is a safe product for intramuscular injection used to treat antibody deficiency conditions and prevent infections like hepatitis A, hepatitis B, measles, chickenpox, rubella, and polio.2

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2 Britannica Sources
  1. therapeutics - Immunoglobulins
  2. infectious disease - HISG

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