hyperfunction

Endocrine hyperfunction occurs when endocrine glands produce excessive amounts of hormones. This can be primary, stemming from an internal gland abnormality, or secondary, a response to changes in regulating substances. In some cases, hyperplastic glands can develop tumors, which are often autonomous and insensitive to feedback control. While most are benign, some are malignant and can spread.1

Hormones are organic substances that regulate physiological activities and maintain homeostasis. They are secreted by glands and travel through the bloodstream to target organs. Hyperfunction can result from intrinsic gland issues like hyperplasia or tumors, or from abnormal stimulation, such as in Graves' disease where antibodies stimulate the thyroid gland. Another example is Cushing disease, caused by a pituitary tumor stimulating the adrenal glands.21