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Horizontal cells are a type of neuron in the retina that play a crucial role in processing visual information. They are located in the outer plexiform layer of the retina and make connections with photoreceptor cells (rods and cones) and bipolar cells.12

The primary function of horizontal cells is to modulate the signals transmitted from photoreceptors to bipolar cells. They achieve this by influencing the activity of neighboring cells, allowing for horizontal transmission of signals across the retina. This lateral interaction helps to enhance contrast and regulate the range of light intensity that bipolar cells respond to, contributing to a more refined visual output.13

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