homogentisate 1,2-dioxygenase References homogentisate 1,2-dioxygenase enzyme Ask Anything Homework Help Written by The Information Architects of Encyclopaedia Britannica The Information Architects maintain a master list of the topics included in the corpus of Encyclopædia Britannica, and create and manage the relationships between them. The Information Architects of Encyclopaedia Britannica Britannica AI Ask Anything Learn about this topic in these articles: alkaptonuria…the liver by the enzyme homogentisate 1,2-dioxygenase. This enzyme is rendered inactive in individuals who have alkaptonuria, owing to mutation of the enzyme’s gene HGD. Read More…the liver by the enzyme homogentisate 1,2-dioxygenase. This enzyme is rendered inactive in individuals who have alkaptonuria, owing to mutation of the enzyme’s gene HGD. Read More