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Homocysteine is an amino acid produced in animal metabolism through the demethylation of methionine. It is represented by the chemical formula C4H9NO2S.1

High levels of homocysteine in the blood have been associated with an increased risk of cardiovascular disease.1

Homocystinuria is a hereditary metabolic disorder related to methionine. In this condition, a defective enzyme prevents the conversion of homocysteine to cystathionine. This leads to elevated concentrations of homocysteine and methionine in the blood plasma. Symptoms can include intellectual disability, lens displacement in the eyes, skeletal deformities, and blood vessel blockages. Dietary therapy may be beneficial.2

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2 Britannica Sources
  1. homocysteine
  2. homocystinuria

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