high-altitude cerebral edema

High-altitude cerebral edema (HACE) is a rare but life-threatening condition that occurs when low air pressure at high altitudes causes blood vessels in the brain to become leaky, leading to fluid buildup. This swelling increases intracranial pressure, reducing oxygen flow to brain cells. Symptoms include shortness of breath, severe headache, nausea, vomiting, confusion, and an inability to walk. HACE requires immediate medical attention and descent to a lower altitude. It is a severe form of altitude sickness, distinct from pulmonary edema, which affects the lungs.12