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hepatocellular jaundice

pathology

Quick Summary

Hepatocellular jaundice is a type of jaundice that occurs when liver cells are severely damaged. This damage impairs the liver's ability to transport bilirubin, a yellow pigment, into the biliary system. As a result, some bilirubin leaks back into the bloodstream, causing the characteristic yellowing of the skin and eyes. This condition is often associated with hepatitis and cirrhosis.1

Jaundice, in general, is the buildup of bilirubin in the body's tissues, leading to a yellow or orange discoloration. It can be caused by an overproduction of bilirubin, defects in the liver's ability to process it, or obstructions in the bile ducts. While jaundice itself is usually not harmful beyond skin discoloration, prolonged cholestatic jaundice can lead to secondary issues like impaired vitamin K absorption and bleeding tendencies.2

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