hematopoietic stem cell

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autologous bone marrow transplant

hematopoietic stem cell

biology

Also known as: HSC

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June 17, 2026

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autologous bone marrow transplant — autologous bone marrow transplant In an autologous bone marrow transplant, hematopoietic stem cells are harvested from the blood or bone marrow of a patient before the patient undergoes treatment for cancer. In order to remove tumour cells that may have been collected with the stem cells, the sample is incubated with antibodies that bind only to stem cells. The stem cells are then isolated and stored for later use, when they are reinfused into the patient.

Hematopoietic stem cells are a type of stem cell found in bone marrow that can produce all types of blood cells and immune system cells. These cells are crucial for replenishing blood cells as needed throughout life. They are also present in smaller amounts in peripheral blood and umbilical cord blood.12

Hematopoietic stem cells are the precursors to various blood cell types, including red blood cells, white blood cells (granulocytes, lymphocytes, monocytes), and platelets. The process of blood cell formation, known as hematopoiesis, originates from these primitive stem cells. In adults, bone marrow is the primary site for this production.234

The ability of hematopoietic stem cells to generate different cell types makes them vital for maintaining health. Transplants of these cells are a recognized therapy for certain immune deficiencies and blood disorders like leukemia. Research is also exploring their potential use in treating conditions such as heart disease and autoimmune disorders.41

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bone marrow transplant
Autologous and allogeneic transplants
…of stem cell therapy, since hematopoietic stem cells from the bone marrow are central to the recovery of the patient receiving the graft. An autologous transplant is used primarily in the case of cancer patients who are preparing to undergo high doses of chemotherapy or radiation therapy. Autologous transplant involves…
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…of stem cell therapy, since hematopoietic stem cells from the bone marrow are central to the recovery of the patient receiving the graft. An autologous transplant is used primarily in the case of cancer patients who are preparing to undergo high doses of chemotherapy or radiation therapy. Autologous transplant involves…
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cryopreservation
…the freezing and storage of hematopoietic stem cells, which are found in the bone marrow and peripheral blood. In autologous bone-marrow rescue, hematopoietic stem cells are collected from a patient’s bone marrow prior to treatment with high-dose chemotherapy. Following treatment, the patient’s cryopreserved cells are thawed and infused back into…
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…the freezing and storage of hematopoietic stem cells, which are found in the bone marrow and peripheral blood. In autologous bone-marrow rescue, hematopoietic stem cells are collected from a patient’s bone marrow prior to treatment with high-dose chemotherapy. Following treatment, the patient’s cryopreserved cells are thawed and infused back into…
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blood
Blood cells
…interleukin-3, stimulates the most ancestral hematopoietic stem cell. Further differentiation of this stem cell into specialized descendants requires particular kinds of CSFs; for example, the CSF erythropoietin is needed for the maturation of red cells, and granulocyte CSF controls the production of granulocytes. These glycoproteins, as well as other CSFs,…
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…interleukin-3, stimulates the most ancestral hematopoietic stem cell. Further differentiation of this stem cell into specialized descendants requires particular kinds of CSFs; for example, the CSF erythropoietin is needed for the maturation of red cells, and granulocyte CSF controls the production of granulocytes. These glycoproteins, as well as other CSFs,…
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multiple sclerosis
Treatment of multiple sclerosis
…the administration of immunosuppressive drugs, hematopoietic stem cells are harvested from the patient’s blood or bone marrow. These cells are then frozen and stored for later reinfusion into the patient following immunosuppressive therapy. Because hematopoietic stem cells have the potential to develop into normally functioning lymphocytes, transplant provides the patient’s…
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…the administration of immunosuppressive drugs, hematopoietic stem cells are harvested from the patient’s blood or bone marrow. These cells are then frozen and stored for later reinfusion into the patient following immunosuppressive therapy. Because hematopoietic stem cells have the potential to develop into normally functioning lymphocytes, transplant provides the patient’s…
Read More