gonad-stimulating substance

biochemistry

Also known as: gamete-shedding substance

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June 29, 2026

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The term "gonad-stimulating substance" refers to gonadotropins, which are hormones produced by the anterior pituitary gland. These hormones regulate the activity of the gonads, the sex glands.

The two primary gonadotropins are luteinizing hormone (LH) and follicle-stimulating hormone (FSH). In males, FSH stimulates sperm development in the testes, while LH stimulates the production of male hormones like testosterone. In females, FSH stimulates the development of egg-containing follicles in the ovaries and the production of estrogens. LH is crucial for ovulation and the production of progesterone.12

Deficiencies in these hormones can lead to hypogonadism, characterized by reduced testosterone and infertility in men.4

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endocrine system
Phylum Echinodermata
A neuropeptide called the gonad-stimulating substance (also called the gamete-shedding substance) is released from the radial nerves into the body cavity about one hour before spawning. Gonad-stimulating substance has been reported in more than 30 species of sea star. This neuropeptide contacts the ovaries directly and causes formation of…
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A neuropeptide called the gonad-stimulating substance (also called the gamete-shedding substance) is released from the radial nerves into the body cavity about one hour before spawning. Gonad-stimulating substance has been reported in more than 30 species of sea star. This neuropeptide contacts the ovaries directly and causes formation of…
Read More