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Goblet cells are specialized epithelial cells found in the lining of various body passages, including the respiratory and digestive tracts. Their primary function is to secrete mucus, a viscous fluid that lubricates and protects these surfaces.1234

In the respiratory system, goblet cells are interspersed among ciliated cells in the airways. The mucus they produce traps inhaled particles like dust and bacteria, which are then moved upward by the cilia and swallowed. In the small intestine, goblet cells are found on the villi and contribute mucin, a key component of mucus, which aids in digestion and absorption. The goblet cell's shape is described as being distended at its free end, resembling an empty goblet after it has released its contents.152

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