glutamate
Quick Summary
Glutamate, also known as glutamic acid, is an amino acid that plays a crucial role in the central nervous system. It is the most abundant amino acid in the brain and functions as an excitatory neurotransmitter. Glutamate is involved in cellular metabolism and is essential for brain function, readily crossing the blood-brain barrier.12
While animals can synthesize glutamate, it is also found in various plant proteins. Glutamine, a related substance, is a monoamide of glutamic acid and is also a common constituent of proteins. Glutamate is important in nerve signaling, with specific receptors like the NMDA receptor mediating its effects.231
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food additiveflavorings…as the amino acid l-glutamate, and monosodium glutamate (MSG) became the first flavor enhancer to be used commercially. The rich flavor associated with l-glutamate was called umami.
Read More…as the amino acid l-glutamate, and monosodium glutamate (MSG) became the first flavor enhancer to be used commercially. The rich flavor associated with l-glutamate was called umami.
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metabolismRemoval of nitrogen…glutamate dehydrogenase, in which the glutamate formed in [26c] is oxidized to α-oxoglutarate, another TCA cycle intermediate [28]. Either NADP+ or both NADP+ and NAD+ may serve as the hydrogen or electron acceptor, depending on the organism, and some organisms synthesize two enzymes, one of which prefers NADP+ and the…
Read More…glutamate dehydrogenase, in which the glutamate formed in [26c] is oxidized to α-oxoglutarate, another TCA cycle intermediate [28]. Either NADP+ or both NADP+ and NAD+ may serve as the hydrogen or electron acceptor, depending on the organism, and some organisms synthesize two enzymes, one of which prefers NADP+ and the…
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nervous systemAmino acidsGlutamate is the most abundant amino acid in the brain. Unlike acetylcholine, glutamate does not vary greatly in concentration from one region to the next. However, the dorsal gray matter of the spinal cord, which contains terminals of incoming dorsal roots, has large concentrations of…
Read MoreGlutamate is the most abundant amino acid in the brain. Unlike acetylcholine, glutamate does not vary greatly in concentration from one region to the next. However, the dorsal gray matter of the spinal cord, which contains terminals of incoming dorsal roots, has large concentrations of…
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