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Gene frequency refers to the ratio of a specific allele's count to the total number of alleles at its genetic locus within a population. This concept is central to population genetics, which studies evolutionary change at the genetic level.123

Allele frequencies, often represented by p for dominant alleles and q for recessive alleles, describe how common different gene variants are within a population. Changes in these frequencies over generations are the basis of evolution.23

Key processes that alter gene frequencies include:
* Mutation: The ultimate source of genetic variation, though it changes frequencies very slowly due to low mutation rates.4
* Natural Selection: Environmental conditions favor certain variants, leading to their increased or decreased prevalence in subsequent generations.23
* Genetic Drift: Random sampling effects, especially significant in smaller populations, can cause allele frequencies to change unpredictably.2

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