gastrinoma
pathology
Quick Summary
A gastrinoma is a tumor that secretes large amounts of the hormone gastrin, leading to a condition called hypergastrinemia. This excess gastrin stimulates the stomach to produce too much gastric acid, causing severe peptic ulcer disease and diarrhea. Gastrinomas can occur as part of multiple endocrine neoplasia type 1 (MEN1) or as a rare disorder known as Zollinger-Ellison syndrome. Treatment typically involves surgically removing the tumor or using medication to reduce gastric acid secretion.1
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