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fructose 6-phosphate

chemical compound

Quick Summary

Fructose 6-phosphate is a chemical compound that plays a role in metabolism, specifically in the breakdown of sugars. It is formed from glucose 6-phosphate through a reaction catalyzed by phosphoglucoisomerase. This transformation involves the oxidation of an alcohol group to a keto group.1

Fructose 6-phosphate is an intermediate in glycolysis, the process by which glucose is broken down to produce energy. It is also involved in gluconeogenesis, the synthesis of glucose from non-carbohydrate precursors. In the liver, fructose 6-phosphate can be converted to fructose 1,6-diphosphate, a step catalyzed by phosphofructokinase, which is important in regulating fermentation. It can also be hydrolyzed to fructose 1-phosphate or converted to glucose 6-phosphate, which is a precursor for storage polysaccharides like starch and glycogen.213

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