fructose 1,6-diphosphate
Quick Summary
Fructose 1,6-diphosphate is a molecule that plays a crucial role in glycolysis, the process by which glucose is broken down to produce energy. It is formed from fructose 6-phosphate and adenosine triphosphate (ATP) through a reaction catalyzed by the enzyme phosphofructokinase. This molecule is then split into two smaller, three-carbon fragments by the enzyme aldolase. Fructose 1,6-diphosphate is also an intermediate in gluconeogenesis, the synthesis of glucose from non-carbohydrate precursors, where it is hydrolyzed to fructose 6-phosphate.123
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metabolismGlycolysisThe product is fructose 1,6-diphosphate [3]. Again, as in the hexokinase reaction, the decrease in free energy of the reaction, which is catalyzed by phosphofructokinase, is sufficiently large to make this reaction virtually irreversible under physiological conditions; ADP is also a product.
Read MoreThe product is fructose 1,6-diphosphate [3]. Again, as in the hexokinase reaction, the decrease in free energy of the reaction, which is catalyzed by phosphofructokinase, is sufficiently large to make this reaction virtually irreversible under physiological conditions; ADP is also a product.
Read More- metabolismFragmentation of other sugars
…fructose 1-phosphate and ATP to fructose 1,6-diphosphate and ADP.
Read More…fructose 1-phosphate and ATP to fructose 1,6-diphosphate and ADP.
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