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A fraction collector is an instrument used in chromatography to collect separated components of a mixture as they exit a column. In elution chromatography, the mobile phase continuously flows through the column, carrying the separated components. A fraction collector, often a rotating tray holding tubes, collects successive samples of the effluent. This process allows for the isolation of relatively large amounts of pure substances for further analysis or manipulation, a technique known as preparative-scale chromatography.1

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