field-flow fractionation
Quick Summary
Field-flow fractionation (FFF) is a separation technique that uses a field applied perpendicular to a flow stream within a narrow channel. Unlike chromatography, FFF does not have a stationary phase. Instead, separation occurs due to the differential migration of substances influenced by the applied field (which can be electrical, thermal, or centrifugal) and the non-uniform velocity of the liquid flow within the channel.123
The primary applications of FFF are for polymers and particulate matter, including biological cells, viruses, and colloids. This method is particularly effective for separating substances in the particle and colloid size range.23
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- chromatographySubsequent developments
This technique is called field-flow fractionation. It has been termed one-phase chromatography because there is no stationary phase. Its main applications are to polymers and particulate matter. The method has been used to separate biological cells, subcellular particles, viruses, liposomes, protein aggregates, fly ash, colloids, and pigments.
Read MoreThis technique is called field-flow fractionation. It has been termed one-phase chromatography because there is no stationary phase. Its main applications are to polymers and particulate matter. The method has been used to separate biological cells, subcellular particles, viruses, liposomes, protein aggregates, fly ash, colloids, and pigments.
Read More - separation and purificationField separations
Field-flow fractionation consists of a series of methods based on a field applied perpendicular to a flow stream in a narrow channel. Because of friction at the channel walls, the velocity of the liquid will be faster in the center than at the walls. In…
Read MoreField-flow fractionation consists of a series of methods based on a field applied perpendicular to a flow stream in a narrow channel. Because of friction at the channel walls, the velocity of the liquid will be faster in the center than at the walls. In…
Read More