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Fibrous proteins are a class of proteins characterized by their elongated, threadlike structure, which is directly related to their function of providing structural support, either rigid or flexible. Unlike globular proteins, fibrous proteins are generally insoluble in water and have high viscosity.12

Key examples of fibrous proteins include:
* Collagen: The most abundant protein in mammals, it is a primary component of bones, tendons, ligaments, skin, and cartilage, providing tensile strength and structural integrity.34
* Keratin: Found in epithelial cells, hair, nails, and feathers, keratin's stability comes from numerous disulfide bonds, making it insoluble and resistant to enzymes.5
* Fibroin: The main protein in silk, it is known for its insolubility and unique amino acid composition.16
* Fibrin: Formed from fibrinogen in blood plasma, it creates insoluble threads that are essential for blood clotting.7

Reticular fibers, composed of collagenous fibrils, also form supportive networks in organs. Fibroblasts are the cells responsible for producing collagen and other connective tissue components.89

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