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Fibroin is an insoluble protein that makes up the filaments of raw silk fiber. It is produced by silkworms as they spin their cocoons. Liquid secretions from glands within the silkworm emerge from a spinneret and harden upon exposure to air, forming twin filaments composed of fibroin. A gummy substance called sericin cements these filaments together. Fibrinogen, a protein found in blood plasma, is converted into insoluble fibrin during the clotting process. Fibrinogen molecules appear as rods and have a high percentage of charged amino acid side chains.123

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