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Fibrinopeptides are small polypeptides released from fibrinogen by the enzyme thrombin during the process of blood clot formation.12

Fibrinogen is a protein found in blood plasma that converts into insoluble fibrin when a clot forms. Thrombin catalyzes the breakage of peptide bonds in fibrinogen, releasing fibrinopeptides. The remaining fibrinogen molecules then form a stable, insoluble fibrin clot. This process is essential for stopping bleeding and is dependent on calcium ions.2

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