Britannica AI Icon

Quick Summary

Fibrin is an insoluble protein that forms the primary component of a blood clot. It is created from fibrinogen, a soluble protein produced by the liver and found in blood plasma. When bleeding occurs due to tissue damage, an enzyme called thrombin converts fibrinogen into fibrin at the wound site. Fibrin molecules then link together to form long threads that trap platelets, creating a spongy mass that hardens and contracts to form a blood clot. This process is essential for stopping blood loss and is a crucial part of coagulation. Hereditary disorders can affect fibrin formation, leading to difficulties in stopping bleeding.123

Summary created from Britannica articles using AI. AI can make mistakes, so verify using Britannica articles.

Ask Britannica AI about this topic

Britannica doesn't have a full article on this topic, so we've curated a list of our relevant coverage.