familial dysbetalipoproteinemia
Quick Summary
Familial dysbetalipoproteinemia, also known as hyperlipoproteinemia type III, is a medical disorder affecting lipid metabolism. It is characterized by increased blood cholesterol and triglycerides due to an abnormality in apoprotein E, a component of lipoproteins. This condition can be inherited as an autosomal recessive or autosomal dominant trait and typically manifests in adulthood.1
Lipoproteins are particles that transport lipids like triglycerides and cholesterol through the blood. Disorders of lipid metabolism can arise from defects in lipoprotein structure, cell receptors, or enzymes, potentially leading to atherosclerosis. Treatment for familial dysbetalipoproteinemia is similar to that for familial hypercholesterolemia and includes dietary changes and medication.1
Ask Britannica AI about this topic
Britannica doesn't have a full article on this topic, so we've curated a list of our relevant coverage.
