exfoliative cytology

medicine

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Last updated

July 17, 2026

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Exfoliative cytology is a medical diagnostic technique that involves the microscopic study of cells shed or obtained from the body. This method is used to determine the presence or absence of conditions, such as cancer.1

Unlike a biopsy, which involves removing tissue, exfoliative cytology examines cells that naturally slough off from body surfaces, like the inside of the mouth. This procedure is quick and simple, making it a valuable alternative to biopsy in specific circumstances, particularly for examining surface cells. However, it often requires further cytological analysis for confirmation of results.2

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biopsy
In exfoliative cytology, cells shed from body surfaces, such as the inside of the mouth, are collected and examined. This technique is useful only for the examination of surface cells and often requires additional cytological analysis to confirm the results.
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In exfoliative cytology, cells shed from body surfaces, such as the inside of the mouth, are collected and examined. This technique is useful only for the examination of surface cells and often requires additional cytological analysis to confirm the results.
Read More