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The esophageal sphincter is a ring of muscles that controls the passage of food and other substances. There are two main esophageal sphincters: the upper and lower esophageal sphincters.

The upper esophageal sphincter is located at the top of the esophagus, near the cricoid cartilage. It is also known as the cricopharyngeus muscle and is composed of striated muscle.

The lower esophageal sphincter (LES) is located at the bottom of the esophagus, where it passes through the diaphragm to connect with the stomach. It is made of smooth muscle and is normally kept closed, relaxing only to allow food to enter the stomach, release gas (belching), or during vomiting. The LES plays a crucial role in preventing stomach contents from refluxing back into the esophagus.1

Disorders of esophageal motility, such as achalasia, can affect the function of these sphincters, leading to difficulty swallowing and impaired emptying of the esophagus.2

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