epithelial mesothelioma
pathology
Quick Summary
Epithelial mesothelioma is a type of cancer that originates in the mesothelium, a protective lining that covers many internal organs and body cavities. This lining is found in the chest cavity (pleura) and the abdominal cavity (peritoneum).1
Key Facts about Epithelial Mesothelioma:
- Origin: Arises from mesothelial cells, which form the pleura and peritoneum.1
- Location: Most commonly develops in the chest (about 75% of cases), but can also occur in the abdomen or, rarely, around the heart or scrotum.1
- Cause: Over 80% of cases are linked to exposure to asbestos. There is typically a long latency period of 20-50 years between exposure and diagnosis.1
- Diagnosis: Often diagnosed at advanced stages due to subtle early symptoms. Pleural effusion (fluid around the lungs) is a common complication leading to diagnosis.1
- Subtypes: Epithelial mesothelioma is the most common subtype, followed by biphasic (mixed) and sarcomatoid types.1
- Treatment: Survival rates are generally poor, with treatments focusing on managing symptoms, surgery, chemotherapy, and radiation therapy.12
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