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The epigenome refers to the chemical compounds that modify the expression and function of an organism's genome. These modifications, which can be heritable or temporary, control how genes are used by cells, influencing development and observable characteristics.

Epigenetic changes allow cells with identical DNA to specialize into different types, such as liver or brain cells. The primary epigenetic modification is methylation, the addition of a methyl group to DNA. Other modifications include histone acetylation, ubiquitination, and phosphorylation.

Aberrant epigenetic changes can lead to disorders and diseases, including certain cancers. Research in epigenomics aims to understand these modifications to develop new diagnostic tools and treatments.123

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  1. epigenetics
  2. epigenome
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