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enterohepatic circulation

physiology

Quick Summary

Enterohepatic circulation is a physiological process where bile acids, synthesized in the liver from cholesterol, are secreted into the small intestine to aid in fat digestion. After performing their function, these bile acids are reabsorbed in the lower small intestine and returned to the liver via the portal vein to be reused. This cycle efficiently recycles about 20 to 30 grams of bile acids daily in humans. A small amount of bile acids that escape this circulation are lost in feces, and the liver synthesizes new ones from cholesterol to replace them. Bile acids also play a role in absorbing fat-soluble vitamins and eliminating excess cholesterol from the body.12

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  1. bile acid
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