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endothelium
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Two cross-sectional illustrations compare a normal human artery with a healthy, open lumen to an artery narrowed by atherosclerotic plaque buildup, showing damaged endothelium, foam cells, fibrous cap, and lipid deposits.
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endothelium: Media

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atherosclerosis
A normal artery compared with an artery affected by atherosclerosis.
Encyclopædia Britannica, Inc.