eicosanoid
Quick Summary
Eicosanoids are a group of signaling molecules derived from 20-carbon polyunsaturated fatty acids, primarily arachidonic acid. These lipid compounds act as local chemical messengers, influencing processes near their site of origin.12
The three main classes of eicosanoids are prostaglandins, thromboxanes, and leukotrienes. They interact with specific cell surface receptors to trigger various effects, including inflammatory responses, changes in blood pressure, and blood clotting. For example, prostaglandins can cause vasodilation, while thromboxanes act as vasoconstrictors. Eicosanoids play crucial roles in physiological processes such as inflammation, smooth muscle contraction, and reproduction. Drugs like aspirin and ibuprofen work by inhibiting the enzymes involved in eicosanoid synthesis or their receptors.12
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