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duplication
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duplication

genetics
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Quick Summary

In genetics, duplication refers to an extra copy of a chromosome region. This can occur spontaneously or due to errors during cell division, such as asymmetrical chromosome pairing or meiotic irregularities. While small duplications within a gene can arise, larger ones are more common.1

Duplications can lead to genomic imbalance, which typically has detrimental effects. However, if a duplication becomes homozygous, it can offer an organism the chance to develop new genetic functions through mutations in the duplicated copy. Gene duplication has been a common occurrence throughout evolution, allowing for the development of new genetic functions. Before a cell divides, it must accurately duplicate its DNA, a process called DNA replication, to ensure its daughter cells receive complete genetic information.123

Summary created from Britannica articles using AI. AI can make mistakes, so verify using Britannica articles.
3 Britannica Sources
  1. cell - Duplication of the genetic material
  2. heredity - Duplications
  3. heredity - DNA phylogeny

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